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target has curated data in GtoImmuPdb
Target id: 1737
Nomenclature: Interleukin-18 receptor 1
| Quaternary Structure: Complexes |
| Interleukin-18 receptor |
Gene and Protein Information  |
||||||
| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
| Human | 1 | 541 | 2q12.1 | IL18R1 | interleukin 18 receptor 1 | |
| Mouse | 1 | 537 | 1 B | Il18r1 | interleukin 18 receptor 1 | |
| Rat | - | - | Il18r1 | interleukin 18 receptor 1 | ||
| Previous and Unofficial Names |
| CD218a | Il18ralpha | IL1RRP | interleukin 18 receptor 1 |
| Database Links |
|
| Alphafold | Q13478 (Hs), Q61098 (Mm) |
| CATH/Gene3D | 2.60.40.10, 3.40.50.10140 |
| ChEMBL Target | CHEMBL4804253 (Hs) |
| Ensembl Gene | ENSG00000115604 (Hs), ENSMUSG00000026070 (Mm), ENSRNOG00000015027 (Rn) |
| Entrez Gene | 8809 (Hs), 16182 (Mm), 301365 (Rn) |
| Human Protein Atlas | ENSG00000115604 (Hs) |
| KEGG Gene | hsa:8809 (Hs), mmu:16182 (Mm), rno:301365 (Rn) |
| OMIM | 604494 (Hs) |
| Pharos | Q13478 (Hs) |
| UniProtKB | Q13478 (Hs), Q61098 (Mm) |
| Wikipedia | IL18R1 (Hs) |
| Immunopharmacology Comments |
| Interleukin-18 1 protein (IL18R1) is the ligand binding subunit of the functional IL-18 receptor heterodimer. |
Immunoglobulin-like family of IL-1 receptors: Interleukin-18 receptor 1. Last modified on 30/10/2017. Accessed on 30/10/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1737.
