Immunoglobulin-like family of IL-1 receptors | Catalytic receptors

Immunoglobulin-like family of IL-1 receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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The immunoglobulin-like family of IL-1 receptors are heterodimeric receptors made up of a cognate receptor subunit and an IL-1 receptor accessory protein, IL1RAP (Q9NPH3, also known as C3orf13, IL-1RAcP, IL1R3). They are characterised by extracellular immunoglobulin-like domains and an intracellular Toll/Interleukin-1R (TIR) domain.

Receptors

Complexes

Interleukin-1 receptor, type I C Show summary »« Hide summary More detailed page

Interleukin-33 receptor C Show summary »« Hide summary More detailed page

Interleukin-36 receptor C Show summary »« Hide summary More detailed page

Interleukin-1 receptor, type II C Show summary »« Hide summary More detailed page

Interleukin-18 receptor C Show summary »« Hide summary More detailed page

Receptors and Subunits

Interleukin 1 receptor, type I C Show summary »« Hide summary More detailed page

Target Id	1734
Nomenclature	Interleukin 1 receptor, type I
Previous and unofficial names	IL1RA \| CD121A \| CD121 antigen-like family member A \| IL-1R-alpha \| interleukin 1 beta receptor type 1 short transmembrane form \| interleukin 1 beta receptor type 1 soluble form \| interleukin 1 bete receptor type 1 long transmembrane form \| interleukin-1 receptor alpha
Complexes	Interleukin-1 receptor, type I
Genes	IL1R1 (Hs), Il1r1 (Mm), Il1r1 (Rn)
Ensembl ID	ENSG00000115594 (Hs), ENSMUSG00000026072 (Mm), ENSRNOG00000014504 (Rn)
UniProtKB AC	P14778 (Hs), P13504 (Mm), Q02955 (Rn)

Interleukin 1 receptor, type II C Show summary »« Hide summary

Interleukin-1 receptor-like 1 C Show summary »« Hide summary More detailed page

Interleukin-1 receptor-like 2 C Show summary »« Hide summary More detailed page

Interleukin-18 1 C Show summary »« Hide summary More detailed page

Accessory Proteins

IL-1 receptor accessory protein Show summary »« Hide summary More detailed page

IL-18 receptor accessory protein Show summary »« Hide summary More detailed page

References

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How to cite this family page

Database page citation:

Immunoglobulin-like family of IL-1 receptors. Accessed on 12/07/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=312.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors. Br J Pharmacol. 172: 5979-6023.