Immunoglobulin-like family of IL-1 receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The immunoglobulin-like family of IL-1 receptors are heterodimeric receptors made up of a cognate receptor subunit and an IL-1 receptor accessory protein, IL1RAP (Q9NPH3, also known as C3orf13, IL-1RAcP, IL1R3). They are characterised by extracellular immunoglobulin-like domains and an intracellular Toll/Interleukin-1R (TIR) domain.

Receptors

Complexes

Interleukin-1 receptor, type I C Show summary » More detailed page

Interleukin-33 receptor C Show summary » More detailed page

Interleukin-36 receptor C Show summary » More detailed page

Interleukin-1 receptor, type II C Show summary » More detailed page

Interleukin-18 receptor C Show summary » More detailed page

Receptors and Subunits

Interleukin 1 receptor, type I C Show summary » More detailed page

Interleukin 1 receptor, type II C Show summary »

Interleukin-1 receptor-like 1 C Show summary » More detailed page

Interleukin-1 receptor-like 2 C Show summary » More detailed page

Interleukin-18 1 C Show summary » More detailed page

Accessory Proteins

IL-1 receptor accessory protein Show summary » More detailed page

IL-18 receptor accessory protein Show summary » More detailed page

References

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How to cite this family page

Database page citation:

Immunoglobulin-like family of IL-1 receptors. Accessed on 27/03/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=312.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors. Br J Pharmacol. 172: 5979-6023.