NLRP5 | NOD-like receptor family | IUPHAR/BPS Guide to PHARMACOLOGY


Target id: 1772

Nomenclature: NLRP5

Family: NOD-like receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for NLRP5 in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 1200 19q13.43 NLRP5 NLR family pyrin domain containing 5
Mouse - 1163 7 10.22 cM Nlrp5 NLR family, pyrin domain containing 5
Rat - - 1q12 Nlrp5 NLR family, pyrin domain containing 5
Previous and Unofficial Names
PAN11 | PYPAF8 | CLR19.8 | MATER | NALP5 | NACHT, leucine rich repeat and PYD containing 5 | NLR family, pyrin domain containing 5 | NLR family
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas
Physiological Functions Comments
Involved in embryonic development
Clinically-Relevant Mutations and Pathophysiology
Disease:  Autoimmune polyendocrinopathy syndrome , type I, with or without reversible metaphyseal dysplasia; APS1
Synonyms: Autoimmune polyendocrine syndrome type 1 [Disease Ontology: DOID:0050167]
Disease Ontology: DOID:0050167
OMIM: 240300


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How to cite this page

Clare Bryant, Tom Monie.
NOD-like receptor family: NLRP5. Last modified on 22/03/2017. Accessed on 16/11/2018. IUPHAR/BPS Guide to PHARMACOLOGY,