Quaternary Structure: Subunits

Interleukin 10 receptor, α subunit (Ligand-binding subunit)

Interleukin 10 receptor, β subunit (Other subunit)

Natural/Endogenous Ligands
IL-10 {Sp: Human}

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Agonists
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Ligand Sp. Action Value Parameter Reference IL-10 {Sp: Human} Hs Agonist - - ⤷

Immunopharmacology Comments

The IL-10 receptor is a heteromeric complex containing two ligand binding α subunits (IL10RA) and two signal-transducing β subunits (IL10RB) [1]. Ligand binding leads to JAK/STAT signalling.