acyloxyacyl hydrolase

Target id: 2873

Nomenclature: acyloxyacyl hydrolase

Family: 3.1.1.- Carboxylic Ester Hydrolases

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: OFF :     Currently no data for acyloxyacyl hydrolase in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 688 7p14.2 AOAH acyloxyacyl hydrolase
Mouse - 574 13 A2 Aoah acyloxyacyl hydrolase
Rat - 574 17q11 Aoah acyloxyacyl hydrolase
Previous and Unofficial Names
acyloxyacyl hydrolase (neutrophil)
Database Links
BRENDA
Ensembl Gene
Entrez Gene
GenitoUrinary Development Molecular Anatomy Project
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction
EC Number: 3.1.1.77

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
JZL195 Hs Inhibition 7.4 pIC50 1
pIC50 7.4 (IC50 4.4x10-8 M) [1]

References

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1. Bachovchin DA, Koblan LW, Wu W, Liu Y, Li Y, Zhao P, Woznica I, Shu Y, Lai JH, Poplawski SE et al.. (2014) A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nat. Chem. Biol.10 (8): 656-63. [PMID:24997602]

How to cite this page

3.1.1.- Carboxylic Ester Hydrolases: acyloxyacyl hydrolase. Last modified on 29/01/2016. Accessed on 12/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2873.