hsp60

Ligand id: 4953

Name: hsp60

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
HSPD1 heat shock protein family D (Hsp60) member 1 Human prepro-60 kDa heat shock protein, mitochondrial GROEL, heat shock 60kDa protein 1 (chaperonin), heat shock 60kD protein 1 (chaperonin), HSP60, spastic paraplegia 13 (autosomal dominant), SPG13
Synonyms
heat shock 60kD protein 1 (chaperonin) | HSP-60 | mitochondrial matrix protein P1
Database Links
CATH/Gene3D 1.10.560.10, 3.50.7.10
Ensembl Gene ENSG00000144381 (Hs)
Human Protein Atlas ENSG00000144381 (Hs)
UniProtKB P10809 (Hs)
Wikipedia HSP60
Comments
HSP60 is a mitochondrial chaperone that is upregulated by immune activation. It is a highly conserved protein, which acts as a major immune modulator in the control of the innate and adaptive immune systems in mammals [1-2].