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Synonyms: heat shock 60kD protein 1 (chaperonin) | HSP-60 | mitochondrial matrix protein P1
Compound class:
Endogenous peptide in human, mouse or rat
Comment: HSP60 is a mitochondrial chaperone that is upregulated by immune activation. It is a highly conserved protein, which acts as a major immune modulator in the control of the innate and adaptive immune systems in mammals [1-2].
Species: Human
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| References |
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1. Landstein D, Ulmansky R, Naparstek Y. (2015)
HSP60: a double edge sword in autoimmunity. Oncotarget, 6 (32): 32299-300. [PMID:26431161] |
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2. Quintana FJ, Cohen IR. (2011)
The HSP60 immune system network. Trends Immunol, 32 (2): 89-95. [PMID:21145789] |
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3. Ulmansky R, Naparstek Y. (2018)
Protective antibodies against HSP60 for autoimmune inflammatory diseases. Clin Immunol, 186: 63. [PMID:28751270] |
