Classification
Compound class	Endogenous peptide in human, mouse or rat
Ligand families/groups	Interferons
Approved drug?	Yes (FDA (1989))

Synonyms

IFN-alpha-2 | interferon alpha-2 | Roferon A®

Comments

IFN-α2 is a type I IFN. The sequence of the recombinant peptide used clinically and known as interferon alfa-2a, is identical to that of human IFN-α2. Interferon alfa-2a has anti-viral, immunomodulatory and antineoplastic actions. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).

Gene/Precursor

Gene symbol Gene name Species Precursor protein name Synonyms IFNA2 interferon alpha 2 Human prepro-interferon alpha-2 alpha-2a interferon, IFNA, IFN-alphaA, interferon, alpha 2, interferon alpha 2b, interferon alpha A

Database Links
Specialist databases
IMGT/mAb-DB	624
Other databases
Ensembl Gene	ENSG00000188379 (Hs)
GtoPdb PubChem SID	178101658
Human Protein Atlas	ENSG00000188379 (Hs)
UniProtKB	P01563 (Hs)
Wikipedia	IFNA2