Classification ![]() |
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Compound class | Endogenous peptide in human, mouse or rat |
Ligand families/groups | Interferons |
Approved drug? | Yes (FDA (1989)) |
Synonyms ![]() |
IFN-alpha-2 | interferon alpha-2 | Roferon A® |
Comments |
IFN-α2 is a type I IFN. The sequence of the recombinant peptide used clinically and known as interferon alfa-2a, is identical to that of human IFN-α2. Interferon alfa-2a has anti-viral, immunomodulatory and antineoplastic actions. It is on the World Health Organization's List of Essential Medicines (link to 2015 list). |
Gene/Precursor ![]() |
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Database Links ![]() |
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Specialist databases | |
IMGT/mAb-DB | 624 |
Other databases | |
Ensembl Gene | ENSG00000188379 (Hs) |
GtoPdb PubChem SID | 178101658 |
Human Protein Atlas | ENSG00000188379 (Hs) |
UniProtKB | P01563 (Hs) |
Wikipedia | IFNA2 |