eptifibatide

Ligand id: 6585

Name: eptifibatide

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: eptifibatide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 20
Hydrogen bond donors 11
Rotatable bonds 11
Topological polar surface area 374.49
Molecular weight 831.32
XLogP 0.89
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1998), EMA (1999))
IUPAC Name
2-[(3R,11S,17S,20S,25aS)-11-(4-carbamimidamidobutyl)-3-carbamoyl-20-(indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo-docosahydro-1H-pyrrolo[2,1-g]1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-17-yl]acetic acid
International Nonproprietary Names
INN number INN
7717 eptifibatide
Synonyms
C68-22 | Eptifibatide Accord (generic) | Integrelin®
Database Links
CAS Registry No. 188627-80-7
ChEMBL Ligand CHEMBL1174
DrugBank Ligand DB00063
GtoPdb PubChem SID 178103198
PubChem CID 448812
Search Google for chemical match using the InChIKey CZKPOZZJODAYPZ-LROMGURASA-N
Search Google for chemicals with the same backbone CZKPOZZJODAYPZ
Search PubMed clinical trials eptifibatide
Search PubMed titles eptifibatide
Search PubMed titles/abstracts eptifibatide
Search UniChem for chemical match using the InChIKey CZKPOZZJODAYPZ-LROMGURASA-N
Search UniChem for chemicals with the same backbone CZKPOZZJODAYPZ
Wikipedia Eptifibatide
Comments
Eptifibatide is a synthetic cyclic hexapeptide inhibitor of the integrin αIIbβ3 protein complex.