eptifibatide

Ligand id: 6585

Name: eptifibatide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 20
Hydrogen bond donors 11
Rotatable bonds 11
Topological polar surface area 374.49
Molecular weight 831.32
XLogP 0.89
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human catalytic receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
integrin αIIbβ3 Inhibitor Inhibition 6.2 – 6.8 pIC50 - 1
pIC50 6.2 – 6.8 (IC50 5.7x10-7 – 1.4x10-7 M) [1]
Description: inhibition of human platelet aggregation. The IC50 varies according to the anti-coagulant used during blood collection.