finasteride

Ligand id: 6818

Name: finasteride

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 58.2
Molecular weight 372.28
XLogP 4.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1992))
IUPAC Name
(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
International Nonproprietary Names
INN number INN
6539 finasteride
Synonyms
MK 906 | MK-906 | MK906 | Propecia® | Proscar®
Database Links
CAS Registry No. 98319-26-7
ChEBI CHEBI:5062
ChEMBL Ligand CHEMBL710 (Hs)
DrugBank Ligand DB01216
GtoPdb PubChem SID 178103424
PubChem CID 57363
RCSB PDB Ligand FIT
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Wikipedia Finasteride
Comments
Inhibits steroid 5-alpha-reductase 2