hydroxyurea

Ligand id: 6822

Name: hydroxyurea

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 1
Topological polar surface area 75.35
Molecular weight 76.03
XLogP -1.61
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1967), EMA (2007))
IUPAC Name
hydroxyurea
International Nonproprietary Names
INN number INN
1991 hydroxycarbamide
Synonyms
Droxia® | Hydrea® | hydroxycarbamide | Siklos® | SQ-1089
Comments
Inhibits ribonucleoside-diphosphate reductase (RR1).
Database Links
CAS Registry No. 127-07-1
ChEMBL Ligand CHEMBL467
DrugBank Ligand DB01005
GtoPdb PubChem SID 178103428
PubChem CID 3657
RCSB PDB Ligand NHY
Search Google for chemical match using the InChIKey VSNHCAURESNICA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VSNHCAURESNICA
Search PubMed clinical trials hydroxycarbamide
Search PubMed titles hydroxycarbamide
Search PubMed titles/abstracts hydroxycarbamide
Search UniChem for chemical match using the InChIKey VSNHCAURESNICA-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone VSNHCAURESNICA
Wikipedia Hydroxyurea