Ligand id: 6822

Name: hydroxyurea

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 3
Rotatable bonds 1
Topological polar surface area 75.35
Molecular weight 76.03
XLogP -1.61
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Shao J, Zhou B, Zhu L, Bilio AJ, Su L, Yuan YC, Ren S, Lien EJ, Shih J, Yen Y. (2005)
Determination of the potency and subunit-selectivity of ribonucleotide reductase inhibitors with a recombinant-holoenzyme-based in vitro assay.
Biochem. Pharmacol., 69 (4): 627-34. [PMID:15670581]