bufexamac

Ligand id: 7498

Name: bufexamac

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 58.56
Molecular weight 223.12
XLogP 2.28
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
Withdrawn drug? Yes
IUPAC Name
2-(4-butoxyphenyl)-N-hydroxyacetamide
International Nonproprietary Names
INN number INN
2557 bufexamac
Synonyms
CP-1044-J3
Paraderm®
Parfenac®
Database Links
CAS Registry No. 2438-72-4
ChEBI CHEBI:31317
ChEMBL Ligand CHEMBL94394
PubChem CID 2466
RCSB PDB Ligand A4Z
Search Google for chemical match using the InChIKey MXJWRABVEGLYDG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MXJWRABVEGLYDG
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Wikipedia Bufexamac
Comments
In addition to inhibition of COX enzymes, this drug has been discovered to inhibit class IIb HDACs (ie HDACs 6 and 10) [1].