AZD1656

Ligand id: 7701

Name: AZD1656

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 128.66
Molecular weight 478.2
XLogP 1.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Withdrawn drug? Yes
IUPAC Name
3-[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy-5-[(2S)-1-methoxypropan-2-yl]oxy-N-(5-methylpyrazin-2-yl)benzamide
Synonyms
AZD 1656 | AZD-1656
Comments
AZD1656 activates glucokinase (GCK; P35557). AZD1656 was developed as a potential treatment for diabetes. This compound is included in AstaZeneca's Open Innovation Pharmacology Toolbox.
Database Links
ChEMBL Ligand CHEMBL3219124
GtoPdb PubChem SID 223366034
PubChem CID 16039797
Search Google for chemical match using the InChIKey FJEJHJINOKKDCW-INIZCTEOSA-N
Search Google for chemicals with the same backbone FJEJHJINOKKDCW
Search UniChem for chemical match using the InChIKey FJEJHJINOKKDCW-INIZCTEOSA-N
Search UniChem for chemicals with the same backbone FJEJHJINOKKDCW