Ligand id: 7701

Name: AZD1656

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 128.66
Molecular weight 478.2
XLogP 1.49
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Pending publication of data, the EC50 value given here is derived from the compound's record in AstaZeneca's Open Innovation Pharmacology Toolbox.
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Glucokinase Hs Activator Activation 7.2 pEC50 - 1
pEC50 7.2 (EC50 5.7x10-8 M) [1]