telotristat ethyl

Ligand id: 9490

Name: telotristat ethyl

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 131.17
Molecular weight 574.17
XLogP 6.32
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2017))
IUPAC Name
ethyl (2S)-2-amino-3-[4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl]phenyl]propanoate
International Nonproprietary Names
INN number INN
9324 telotristat
Synonyms
LX-1606 | LX1606 | Xermelo®
Comments
Telotristat ethyl is an oral tryptophan hydroxylase inhibitor. Telotristat ethyl is the USAN, the INN is telotristat (represented in PubChem CID 25025298.
Database Links
CAS Registry No. 1033805-22-9 (source: PubChem)
ChEMBL Ligand CHEMBL2105695
GtoPdb PubChem SID 329968430
PubChem CID 25181577
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