Ligand id: 1135

Name: exendin-4

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Binds to the GLP-1 receptor.
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
GLP-1 receptor Hs Agonist Full agonist 8.7 – 9.0 pKi - 2
pKi 8.7 – 9.0 (Ki 1.99x10-9 – 1x10-9 M) [2]
GLP-1 receptor Hs Agonist Agonist 9.2 pIC50 - 3
pIC50 9.2 (IC50 6.6x10-10 M) [3]
Description: Displacement of GLP-1 from hGLP-1 receptor expressed in CHOK1 cells by exendin-4