exendin-4

Ligand id: 1135

Name: exendin-4

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Binds to the GLP-1 receptor.
Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
GLP-1 receptor Agonist Full agonist 8.7 – 9.0 pKi - 2
pKi 8.7 – 9.0 (Ki 1.99x10-9 – 1x10-9 M) [2]
GLP-1 receptor Agonist Agonist 9.2 pIC50 - 3
pIC50 9.2 (IC50 6.6x10-10 M) [3]
Description: Displacement of GLP-1 from hGLP-1 receptor expressed in CHOK1 cells by exendin-4