chlorzoxazone

Ligand id: 2322

Name: chlorzoxazone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 38.33
Molecular weight 168.99
XLogP 1.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
KCa3.1 Activator Agonist 4.0 pEC50 - 2
pEC50 4.0 (EC50 1x10-4 M) [2]
Voltage: -100.0 mV
Selectivity at rat ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
KCa2.2 Activator - 3.0 – 4.1 pEC50 - 1-2
pEC50 3.0 – 4.1 [1-2]