chlorzoxazone

Ligand id: 2322

Name: chlorzoxazone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 38.33
Molecular weight 168.99
XLogP 1.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Cao Y, Dreixler JC, Roizen JD, Roberts MT, Houamed KM. (2001)
Modulation of recombinant small-conductance Ca(2+)-activated K(+) channels by the muscle relaxant chlorzoxazone and structurally related compounds.
J. Pharmacol. Exp. Ther.296 (3): 683-9. [PMID:11181893]
2. Syme CA, Gerlach AC, Singh AK, Devor DC. (2000)
Pharmacological activation of cloned intermediate- and small-conductance Ca(2+)-activated K(+) channels.
Am. J. Physiol., Cell Physiol.278 (3): C570-81. [PMID:10712246]