nicorandil

Ligand id: 2411

Name: nicorandil

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 94.36
Molecular weight 211.06
XLogP 0.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Kir6.2 Activator - - - -
Selectivity at mouse ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Kir6.1 Activator Agonist - - 3x10-4 2
Conc range: 3x10-4 M [2]
Voltage: -60.0 – 60.0 mV