isoflurane

Ligand id: 2505

Name: isoflurane

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 9.23
Molecular weight 183.97
XLogP 2.6
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human ion channels
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Target Type Action Affinity Units Concentration range (M) Reference
K2P2.1 Activator - - - - 2
studied at 1-5 mM [2]
Selectivity at rat ion channels
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Target Type Action Affinity Units Concentration range (M) Reference
TRPA1 Activator Activation 3.7 pEC50 - 1
pEC50 3.7 [1]
Description: Patch clamp
Conditions: HEK293 cells expressing rat TRPA1
Ligand mentioned in the following text fields