clofilium

Ligand id: 2507

Name: clofilium

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 0
Rotatable bonds 13
Topological polar surface area 0
Molecular weight 338.26
XLogP 7.64
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human ion channels
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
KNa1.1 Channel blocker Antagonist - - 1.09x10-4 1
Conc range: 1.09x10-4 M [1]
KNa1.2 Channel blocker Antagonist - - 1.09x10-4 1
Conc range: 1.09x10-4 M [1]
Kv1.5 Channel blocker - 6.9 pIC50 - 3
pIC50 6.9 [3]
Kv10.1 Channel blocker - 6.6 pIC50 - 2
pIC50 6.6 [2]