dobutamine

Ligand id: 535

Name: dobutamine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 4
Rotatable bonds 7
Topological polar surface area 72.72
Molecular weight 301.17
XLogP 3.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
β2-adrenoceptor Agonist Partial agonist 6.2 pKi - 2
pKi 6.2 [2]
β1-adrenoceptor Agonist Partial agonist 5.5 pKi - 1
pKi 5.5 [1]
Ligand mentioned in the following text fields