Synonyms: CCG 977 | CCG977
Compound class:
Synthetic organic
Comment: CCG-977 is an analogue of CCG 1423, both of which inhibit RhoA transcriptional signaling via an unkown mechanism of action. Both are tool compounds for disrupting the transcriptional responses of the Rho pathway in cancer.
|
|
Bioactivity Comments |
CCG-977 inhibits Gα13Q226L-stimulated SRE.L luciferase expression in PC-3 cells with an IC50 of 5 uM [1]. |