Ligand id: 6762

Name: CCG-977

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 83.65
Molecular weight 522.02
XLogP 7.29
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Evelyn CR, Wade SM, Wang Q, Wu M, Iñiguez-Lluhí JA, Merajver SD, Neubig RR. (2007)
CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling.
Mol. Cancer Ther., 6 (8): 2249-60 Open access. [PMID:17699722]