eculizumab

Ligand id: 6884

Name: eculizumab

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Eculizumab binds to and blocks the cleavage of the complement protein C5, thereby preventing the formation of C5a.
Selectivity at human ligand targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
complement C5 Antibody Binding 10.5 pKd - 1
pKd 10.5 (Kd 3x10-11 M) [1]