Ligand id: 6884

Name: eculizumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Eculizumab binds to and blocks the cleavage of the complement protein C5, thereby preventing the formation of C5a.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
complement C5 Hs Antibody Binding 10.5 pKd - 1
pKd 10.5 (Kd 3x10-11 M) [1]