eculizumab

Ligand id: 6884

Name: eculizumab

Classification
Compound class Antibody
Approved drug? Yes (FDA (2011), EMA (2007))
International Nonproprietary Names
INN number INN
8231 eculizumab
Synonyms
h5G1.1 | h5G1.1VHC | Soliris®
Database Links
Specialist databases
IMGT/mAb-DB 37
Other databases
PubChem SID 178103466
Search PubMed clinical trials eculizumab
Search PubMed titles eculizumab
Search PubMed titles/abstracts eculizumab
Wikipedia Eculizumab
Comments
Eculizumab is a humanized monoclonal antibody targeting terminal complement activation, by binding to complement component C5 and inhibiting the production of C5a. It is the first approved therapy for paroxysmal nocturnal hemoglobinuria.