Ligand id: 6896

Name: forasartan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 98.06
Molecular weight 416.24
XLogP 7.18
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Due to the polypharmacology of this drug we have not mapped it to a primary target.
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
AT1 receptor Antagonist Antagonist 8.2 – 8.6 pIC50 - 2
pIC50 8.2 – 8.6 (IC50 6.9x10-9 – 2.8x10-9 M) [2]