Ligand id: 6896

Name: forasartan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 98.06
Molecular weight 416.24
XLogP 7.18
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Olins GM, Chen ST, McMahon EG, Palomo MA, Reitz DB. (1995)
Elucidation of the insurmountable nature of an angiotensin receptor antagonist, SC-54629.
Mol. Pharmacol., 47 (1): 115-20. [PMID:7838120]
2. Olins GM, Corpus VM, Chen ST, McMahon EG, Palomo MA, McGraw DE, Smits GJ, Null CL, Brown MA, Bittner SE et al.. (1993)
Pharmacology of SC-52458, an orally active, nonpeptide angiotensin AT1 receptor antagonist.
J. Cardiovasc. Pharmacol., 22 (4): 617-25. [PMID:7505365]