Ligand id: 6971

Name: oprelvekin

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Recombinant human IL-11 promotes cellular proliferation of Ba/F3 cells exogenously expressing IL-11 receptors, with an EC50 value of 2.5ng/mL [2], so it would be expected that oprelvekin would have similar activity.
Selectivity at Human catalytic receptors
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Target Type Action Affinity Units Concentration range (M) Reference
Interleukin-11 receptor Agonist Full agonist - - - 1,3