oprelvekin

Ligand id: 6971

Name: oprelvekin

No information available.
Summary of Clinical Use
This drug is used to increase platelet counts in patients receiving chemotherapy, to circumvent drug-induced thrombocytopenia.
Mechanism Of Action and Pharmacodynamic Effects
Oprelvekin binds to the interleukin 11 receptor inducing thrombopoietic events including proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induction of megakaryocyte maturation, which culminate in increased platelet production.
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