ethinylestradiol

Ligand id: 7071

Name: ethinylestradiol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 40.46
Molecular weight 296.18
XLogP 4.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human nuclear hormone receptors
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Target Type Action Affinity Units Concentration range (M) Reference
Estrogen receptor-α Agonist Agonist 8.7 pIC50 - 1
pIC50 8.7 (IC50 2x10-9 M) [1]
Estrogen receptor-β Agonist Agonist 8.1 pIC50 - 1
pIC50 8.1 (IC50 8.1x10-9 M) [1]