Estrogen receptor-α

Nomenclature: Estrogen receptor-α

Systematic Nomenclature: NR3A1

Family: Steroid hormone receptors

Annotation status:  image of a green circle Annotated and expert reviewed. Please contact us if you can help with updates.  » Email us

Gene and Protein Information
Species AA Chromosomal Location Gene Symbol Gene Name Reference
Human 595 6q25.1 ESR1 estrogen receptor 1 9
Mouse 599 10 12.0 cM Esr1 estrogen receptor 1 (alpha) 30
Rat 600 1q12 Esr1 estrogen receptor 1 14
Previous and Unofficial Names
ERα
Era
Oestrogen α
Estradiol
ESR
NR3A1
ER-alpha
Er alpha
RNESTROR
Estrogen receptor alpha
estradiol receptor
estrogen receptor
estrogen receptor 1 (alpha)
estrogen receptor alpha variant delta 4
estrogen receptor protein
nuclear receptor subfamily 3 group A member 1
ER[a]
ERalpha
Estr
Estra
AA420328
AU041214
Database Links
ChEMBL Target
DrugBank Target
Ensembl Gene
Entrez Gene
GeneCards
GenitoUrinary Development Molecular Anatomy Project
HomoloGene
Human Protein Reference Database
InterPro
KEGG Gene
NURSA Receptor
OMIM
Orphanet Gene
PharmGKB Gene
PhosphoSitePlus
RefSeq Nucleotide
RefSeq Protein
TreeFam
UniProtKB
Wikipedia
Selected 3D Structures
Image of receptor 3D structure from RCSB PDB
Description:  Estrogen receptor alpha - Ligand binding domain
PDB Id:  3ERT
Ligand:  4-hydroxy​tamoxifen
Resolution:  1.9Å
Species:  Human
References:  23
Natural/Endogenous Ligands
17β-estradiol
Agonists
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
diethylstilbestrol Hs Agonist 10.4 pKi 16
pKi 10.4 [16]
4-hydroxy​tamoxifen Hs Agonist 9.85 pKi 16
pKi 9.85 [16]
17β-estradiol Hs Agonist 9.82 pKi 16
pKi 9.82 [16]
PPT Hs Agonist 9.64 pKi 15,25
pKi 9.64 [15,25]
raloxifene Hs Agonist 9.5 pKi 25
pKi 9.5 [25]
estriol Hs Agonist 8.67 pKi 16
pKi 8.67 [16]
estrone Hs Agonist 8.5 pKi 16
pKi 8.5 [16]
R,R-THC Hs Agonist 8.38 pKi 27
pKi 8.38 [27]
tamoxifen Hs Agonist 7.82 pKi 16
pKi 7.82 [16]
ethinyl estradiol Hs Agonist 8.7 pIC50 12
pIC50 8.7 (IC50 2x10-9 M) [12]
lasofoxifene Hs Partial agonist 8.51 pIC50 20
pIC50 8.51 (IC50 3.1x10-9 M) [20]
Agonist Comments
Tamoxifen is classified as a mixed agonist/antagonist ligand for this receptor [16].
Antagonists
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Affinity Units Reference
hexestrol Hs Antagonist 10.3 pKi 16
pKi 10.3 [16]
4-hydroxy​tamoxifen Hs Antagonist 9.85 pKi 16
pKi 9.85 [16]
raloxifene Hs Antagonist 9.5 pKi 16
pKi 9.5 [16]
fulvestrant Hs Antagonist 8.98 pKi 22
pKi 8.98 (Ki 1.04x10-9 M) [22]
clomiphene Hs Antagonist 8.89 pKi 1
pKi 8.89 (Ki 1.3x10-9 M) [1]
methyl-piperidino-pyrazole Hs Antagonist 8.57 pKi 26
pKi 8.57 (Ki 2.7x10-9 M) [26]
tamoxifen Hs Antagonist 7.8 pKi 16
pKi 7.8 [16]
bazedoxifene Hs Antagonist 7.64 pIC50 18
pIC50 7.64 (IC50 2.3x10-8 M) [18]
DNA Binding
Structure:  Homodimer
HRE core sequence:  GGTCAnnnTGACC
Response element:  ERE, Half site, Palindrome
Co-binding Partners
Name Interaction Effect Reference
HSP90 Physical, Functional Cellular localization, DNA binding 6
AP1 Physical, Functional Transcriptional activation 28
SP1 Physical, Functional DNA binding, Transcriptional activation 21
Main Co-regulators
Name Activity Specific Ligand dependent AF-2 dependent Comments References
NCOA1 Co-activator No Yes Yes 11
NCOA2 Co-activator No Yes Yes 11
NCOA3 Co-activator No Yes Yes 11
CREBBP Co-activator No Yes Yes 11
EP300 Co-activator No Yes Yes 11
MED1 Co-activator No Yes Yes 11
DDX5 Co-activator No Yes No 11
SRA1 Co-activator No Yes No 11
NCOR1 Co-repressor No Yes No 11
NRIP1 Co-repressor No Yes Yes Competes with AF-2 cofactor binding 11
Main Target Genes
Name Species Effect Technique Comments References
TFF1 Human Activated ChIP, Transient transfection, EMSA 2
PGR Human Activated Footprint, Transient transfection,EMSA 19
CTSD Human Activated Transient transfection, EMSA 29
LFT Human Activated Footprint, Transient transfection,ChIP 10
Tissue Distribution
Endometrium, liver, white adipose tissue, breast, bone, central and peripheral nervous system, ovary, CV system, brain, testes, prostate, epididymis
Species:  Human
Technique:  Northern, Q-PCR, in situ, Western, immunohistology and other
References: 
Tissue Distribution Comments
Similar patterns are seen in mice and rats.
Functional Assays
Vaginal cornification
Species:  Mouse
Tissue: 
Response measured: 
References:  4
Uterotrophic assay
Species:  Mouse
Tissue:  Uterus
Response measured: 
References:  13
HGP Axis (Gonadotropin suppression)
Species:  Human
Tissue: 
Response measured: 
References:  5
Phenotypes, Alleles and Disease Models Mouse data from MGI

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Allele Composition & genetic background Accession Phenotype Id Phenotype Reference
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6N
MGI:1352467  MP:0002144 abnormal B cell differentiation PMID: 10875230 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002458 abnormal B cell number PMID: 12603601 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0002458 abnormal B cell number PMID: 12603601 
Esr1tm1.1Pws Esr1tm1.1Pws/Esr1tm1.1Pws
involves: C57BL/6 * CBA
MGI:1352467  MP:0004883 abnormal blood vessel healing PMID: 20577047 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0000172 abnormal bone marrow cell number PMID: 12603601 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0000172 abnormal bone marrow cell number PMID: 9647203 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0000172 abnormal bone marrow cell number PMID: 12603601 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002896 abnormal bone mineralization PMID: 15283680 
Ctsk+|Ctsktm1(cre)Ska|Esr1tm1Mma Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:107823  MGI:1352467  MP:0002896 abnormal bone mineralization PMID: 17803905 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6
MGI:1352467  MP:0002896 abnormal bone mineralization PMID: 16234973 
Esr1tm1.1Lja|Esr1tm1.1Mma Esr1tm1.1Lja/Esr1tm1.1Mma
involves: 129P2/OlaHsd * 129S2/SvPas * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0002896 abnormal bone mineralization PMID: 16234973 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008271 abnormal bone ossification PMID: 15283680 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0003795 abnormal bone structure PMID: 15283680 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0003795 abnormal bone structure PMID: 16234973 
Esr1tm1.1Lja|Esr1tm1.1Mma Esr1tm1.1Lja/Esr1tm1.1Mma
involves: 129P2/OlaHsd * 129S2/SvPas * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0003795 abnormal bone structure PMID: 16234973 
Esr1tm1.1Scma|Lyz2+|Lyz2tm1(cre)Ifo Esr1tm1.1Scma/Esr1tm1.1Scma,Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
MGI:1352467  MGI:96897  MP:0003795 abnormal bone structure PMID: 20053716 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0000662 abnormal branching of the mammary ductal tree PMID: 12351685 
Esr1tm1Sakh|Tg(MMTV-cre)4Mam Esr1tm1Sakh/Esr1tm1Sakh,Tg(MMTV-cre)4Mam/?
involves: 129P2/OlaHsd * C57BL/6 * FVB
MGI:1352467  MGI:2176163  MP:0000662 abnormal branching of the mammary ductal tree PMID: 17785410 
Esr1tm1Sakh|Tg(Wap-cre)11738Mam Esr1tm1Sakh/Esr1tm1Sakh,Tg(Wap-cre)11738Mam/?
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:2176164  MP:0000662 abnormal branching of the mammary ductal tree PMID: 17785410 
Esr1tm1.1Scma|Lyz2+|Lyz2tm1(cre)Ifo Esr1tm1.1Scma/Esr1tm1.1Scma,Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
MGI:1352467  MGI:96897  MP:0000130 abnormal cancellous bone morphology PMID: 20053716 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0009780 abnormal chondrocyte physiology PMID: 14753739 
Apoetm1Bres|Esr1tm1Ksk Apoetm1Bres/Apoetm1Bres,Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Apoe Esr1
MGI:1352467  MGI:88057  MP:0000180 abnormal circulating cholesterol level PMID: 11160157 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0005416 abnormal circulating protein level PMID: 10805804 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0005416 abnormal circulating protein level PMID: 10805804 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0004816 abnormal class switch recombination PMID: 12603601 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0004816 abnormal class switch recombination PMID: 12603601 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0003796 abnormal cortical bone morphology PMID: 10805804  15283680 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0003796 abnormal cortical bone morphology PMID: 10805804 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0004728 abnormal efferent ductules of testis PMID: 10670526 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0004896 abnormal endometrium morphology PMID: 11311804 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0004896 abnormal endometrium morphology PMID: 17046690 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0004933 abnormal epididymis epithelium morphology PMID: 10670526  9393999 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002631 abnormal epididymis morphology PMID: 8895349 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0002631 abnormal epididymis morphology PMID: 10670526 
Esr1tm1.2Mma|Tg(Cga-cre)3Sac Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cga-cre)3Sac/0
involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL
MGI:1352467  MGI:2180056  MP:0001927 abnormal estrous cycle PMID: 17947360 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0001927 abnormal estrous cycle PMID: 19439729 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0001927 abnormal estrous cycle PMID: 19423761 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0001119 abnormal female reproductive system morphology PMID: 18953638 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0003699 abnormal female reproductive system physiology PMID: 8248223 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0005209 abnormal gastric mucosa morphology PMID: 12855748 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0008868 abnormal granulosa cell morphology PMID: 18953638 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6N
MGI:1352467  MP:0002123 abnormal hematopoiesis PMID: 10875230 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0000607 abnormal hepatocyte morphology PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0000837 abnormal hypothalamus morphology PMID: 9391155 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002490 abnormal immunoglobulin level PMID: 12603601 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0002490 abnormal immunoglobulin level PMID: 12603601 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002184 abnormal innervation PMID: 11311804 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0009205 abnormal internal male genitalia morphology PMID: 8723431 
Esr1+|Esr1tm1Ksk Esr1tm1Ksk/Esr1+
involves: 129P2/OlaHsd
MGI:1352467  MP:0009205 abnormal internal male genitalia morphology PMID: 8723431 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002136 abnormal kidney physiology PMID: 14745006 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0006315 abnormal kidney protein excretion PMID: 17495854 
Esr1tm1Sakh|Tg(Wap-cre)11738Mam Esr1tm1Sakh/Esr1tm1Sakh,Tg(Wap-cre)11738Mam/?
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:2176164  MP:0001882 abnormal lactation PMID: 17785410 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0003055 abnormal long bone epiphyseal plate morphology PMID: 14753739 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0003969 abnormal luteinizing hormone level PMID: 17046690 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0003969 abnormal luteinizing hormone level PMID: 19439729 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008828 abnormal lymph node cell ratio PMID: 14745006 
Esr1tm1.1Scma|Lyz2+|Lyz2tm1(cre)Ifo Esr1tm1.1Scma/Esr1tm1.1Scma,Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
MGI:1352467  MGI:96897  MP:0002451 abnormal macrophage physiology PMID: 20053716 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0001145 abnormal male reproductive system morphology PMID: 18953638 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0003698 abnormal male reproductive system physiology PMID: 9393999 
Esr1tm1Sakh|Tg(Wap-cre)11738Mam Esr1tm1Sakh/Esr1tm1Sakh,Tg(Wap-cre)11738Mam/?
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:2176164  MP:0009506 abnormal mammary gland alveolus morphology PMID: 17785410 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0000628 abnormal mammary gland development PMID: 10919287 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0000628 abnormal mammary gland development PMID: 18339713 
Esr1tm2.1Gsc Esr1tm2.1Gsc/Esr1tm2.1Gsc
involves: 129P2/OlaHsd * C57BL/6
MGI:1352467  MP:0000628 abnormal mammary gland development PMID: 19574448 
Esr1tm1Ksk|Tg(Wnt1)1Hev Esr1tm1Ksk/Esr1tm1Ksk,Tg(Wnt1)1Hev/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:1890060  MP:0000628 abnormal mammary gland development PMID: 10213494 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MP:0000628 abnormal mammary gland development PMID: 10213494 
Esr1tm1Ksk|Tg(MMTV-Erbb2)NK1Mul Esr1tm1Ksk/Esr1tm1Ksk,Tg(MMTV-Erbb2)NK1Mul/0
involves: 129P2/OlaHsd * C57BL/6J * FVB/N
MGI:1352467  MGI:3513809  MP:0000628 abnormal mammary gland development PMID: 12019156 
Esr1tm1Sakh|Tg(Wap-cre)11738Mam Esr1tm1Sakh/Esr1tm1Sakh,Tg(Wap-cre)11738Mam/?
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:2176164  MP:0000627 abnormal mammary gland morphology PMID: 17785410 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001386 abnormal maternal nurturing PMID: 9832446 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001376 abnormal mating receptivity PMID: 8248223  9832446 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0005327 abnormal mesangial cell PMID: 17495854 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008487 abnormal mesonephros morphology PMID: 11014235 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0002108 abnormal muscle morphology PMID: 8723431 
Esr1+|Esr1tm1Ksk Esr1tm1Ksk/Esr1+
involves: 129P2/OlaHsd
MGI:1352467  MP:0002108 abnormal muscle morphology PMID: 8723431 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0008256 abnormal myometrium morphology PMID: 18953638 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0002736 abnormal nociception after inflammation PMID: 19285805 
Ctsk+|Ctsktm1(cre)Ska|Esr1tm1Mma Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:107823  MGI:1352467  MP:0001541 abnormal osteoclast physiology PMID: 17803905 
Esr1tm1.1Lja|Esr1tm1.1Mma Esr1tm1.1Lja/Esr1tm1.1Mma
involves: 129P2/OlaHsd * 129S2/SvPas * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0001541 abnormal osteoclast physiology PMID: 16234973 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0001131 abnormal ovarian follicle morphology PMID: 10976058 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0001131 abnormal ovarian follicle morphology PMID: 10976058 
Esr1tm1.2Mma|Tg(Cga-cre)3Sac Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cga-cre)3Sac/0
involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL
MGI:1352467  MGI:2180056  MP:0001131 abnormal ovarian follicle morphology PMID: 17947360 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0001131 abnormal ovarian follicle morphology PMID: 19439729 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0008871 abnormal ovarian follicle number PMID: 19423761 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0001130 abnormal ovarian folliculogenesis PMID: 10976058 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001126 abnormal ovary morphology PMID: 8248223 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0001126 abnormal ovary morphology PMID: 10600740 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0001126 abnormal ovary morphology PMID: 10919287 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0001126 abnormal ovary morphology PMID: 17046690 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0001126 abnormal ovary morphology PMID: 12351685 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0001126 abnormal ovary morphology PMID: 10976058 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0001126 abnormal ovary morphology PMID: 10976058 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0001126 abnormal ovary morphology PMID: 18953638 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0001126 abnormal ovary morphology PMID: 19423761 
Esr1tm1Ksk|Esr2tm1Unc|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0001126 abnormal ovary morphology PMID: 12855748 
Esr1tm1Ksk|Esr2tm1Unc|Inha+|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inha+
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0001126 abnormal ovary morphology PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0008872 abnormal physiological response to xenobiotic PMID: 18317592 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0005646 abnormal pituitary gland physiology PMID: 9171231 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0009362 abnormal primary ovarian follicle morphology PMID: 18953638 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0009361 abnormal primordial ovarian follicle morphology PMID: 18953638 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0009736 abnormal prostate gland branching morphogenesis PMID: 18755802 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0003607 abnormal prostate gland physiology PMID: 18755802 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001384 abnormal pup retrieval PMID: 9832446 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0005325 abnormal renal glomerulus morphology PMID: 17495854 
Esr1tm1.1Pws Esr1tm1.1Pws/Esr1tm1.1Pws
involves: C57BL/6 * CBA
MGI:1352467  MP:0002160 abnormal reproductive system morphology PMID: 20577047 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0001919 abnormal reproductive system physiology PMID: 18953638 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 12603601 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 17495854  18063692 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 18339713 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 10976058 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 10976058 
Esr1+|Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1+,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 10976058 
Esr1tm1.1Mma|Esr2+|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2+
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 10976058 
Esr1tm1Arnal Esr1tm1Arnal/Esr1tm1Arnal
involves: C57BL/6
MGI:1352467  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 19188600 
Esr1tm1.1Mma|Ldlrtm1Her Esr1tm1.1Mma/Esr1tm1.1Mma,Ldlrtm1Her/Ldlrtm1Her
involves: 129S2/SvPas * 129S7/SvEvBrd
MGI:1352467  MGI:96765  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 19188600 
Esr1tm1Arnal|Ldlrtm1Her Esr1tm1Arnal/Esr1tm1Arnal,Ldlrtm1Her/Ldlrtm1Her
involves: 129S7/SvEvBrd
MGI:1352467  MGI:96765  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 19188600 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0003638 abnormal response/metabolism to endogenous compounds PMID: 11557741  12603601 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0006416 abnormal rete testis morphology PMID: 10976058 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0006416 abnormal rete testis morphology PMID: 10976058 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0009363 abnormal secondary ovarian follicle morphology PMID: 17046690 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0009363 abnormal secondary ovarian follicle morphology PMID: 18339713 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0009363 abnormal secondary ovarian follicle morphology PMID: 12351685 
Esr1+|Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1+,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0009363 abnormal secondary ovarian follicle morphology PMID: 10976058 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0006304 abnormal seminiferous epithelium morphology PMID: 8895349 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002216 abnormal seminiferous tubule morphology PMID: 8895349 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0002216 abnormal seminiferous tubule morphology PMID: 10976058 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0002216 abnormal seminiferous tubule morphology PMID: 10976058 
Esr1tm1Ksk|Esr2tm1Unc|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0002216 abnormal seminiferous tubule morphology PMID: 12855748 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0002784 abnormal Sertoli cell morphology PMID: 10976058 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0002566 abnormal sexual interaction PMID: 11114183 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0002113 abnormal skeleton development PMID: 14753739 
Esr1tm1.1Scma|Lyz2+|Lyz2tm1(cre)Ifo Esr1tm1.1Scma/Esr1tm1.1Scma,Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
MGI:1352467  MGI:96897  MP:0002113 abnormal skeleton development PMID: 20053716 
Esr1tm1.1Scma|Lyz2+|Lyz2tm1(cre)Ifo Esr1tm1.1Scma/Esr1tm1.1Scma,Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
MGI:1352467  MGI:96897  MP:0001533 abnormal skeleton physiology PMID: 20053716 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001156 abnormal spermatogenesis PMID: 8895349 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008737 abnormal spleen physiology PMID: 14745006 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0000473 abnormal stomach glandular epithelium morphology PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0009648 abnormal superovulation PMID: 10342864 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0009648 abnormal superovulation PMID: 19423761 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0001146 abnormal testis morphology PMID: 10670526  8723431 
Esr1+|Esr1tm1Ksk Esr1tm1Ksk/Esr1+
involves: 129P2/OlaHsd
MGI:1352467  MP:0001146 abnormal testis morphology PMID: 8723431 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0004850 abnormal testis weight PMID: 9393999 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0009365 abnormal theca folliculi PMID: 17046690 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0009365 abnormal theca folliculi PMID: 19423761 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6N
MGI:1352467  MP:0003763 abnormal thymus physiology PMID: 10510352 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001120 abnormal uterus morphology PMID: 11311804 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0001120 abnormal uterus morphology PMID: 18339713 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0009671 abnormal uterus physiology PMID: 12351685 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0004903 abnormal uterus weight PMID: 11557741 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0001140 abnormal vagina epithelium morphology PMID: 11784006 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0001139 abnormal vagina morphology PMID: 18339713 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0000137 abnormal vertebrae morphology PMID: 14753739 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0000137 abnormal vertebrae morphology PMID: 14753739 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001134 absent corpus luteum PMID: 8248223 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0001134 absent corpus luteum PMID: 10600740 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0001134 absent corpus luteum PMID: 10342864  10919287 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0001134 absent corpus luteum PMID: 17046690 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0001134 absent corpus luteum PMID: 18339713 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0001134 absent corpus luteum PMID: 12351685 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0001134 absent corpus luteum PMID: 10976058 
Esr1+|Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1+,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0001134 absent corpus luteum PMID: 10976058 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0001134 absent corpus luteum PMID: 18953638 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0001134 absent corpus luteum PMID: 19439729 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0009097 absent endometrial glands PMID: 17046690 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0009009 absent estrous cycle PMID: 10976058 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6
MGI:1352467  MP:0004484 altered response of heart to induced stress PMID: 10775144 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0008869 anovulation PMID: 10919287 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0008869 anovulation PMID: 18339713 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002675 asthenozoospermia PMID: 8895349 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0002675 asthenozoospermia PMID: 10600740 
Apoetm1Bres|Esr1tm1Ksk Apoetm1Bres/Apoetm1Bres,Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Apoe Esr1
MGI:1352467  MGI:88057  MP:0005338 atherosclerotic lesions PMID: 11160157 
Esr1tm1Ksk|Esr2tm1Unc|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0005150 cachexia PMID: 12855748 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0005150 cachexia PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0000523 cortical renal glomerulopathies PMID: 14745006 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0005656 decreased aggression PMID: 9037078 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0003862 decreased aggression towards males PMID: 11114183 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0003862 decreased aggression towards males PMID: 11114183 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6N
MGI:1352467  MP:0005017 decreased B cell number PMID: 10875230 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0009674 decreased birth weight PMID: 11070086 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0001258 decreased body length PMID: 14753739 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001262 decreased body weight PMID: 10805804 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0001262 decreased body weight PMID: 10805804 
Esr1tm1Ksk|Esr2tm1Unc|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0001262 decreased body weight PMID: 12855748 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0001262 decreased body weight PMID: 12855748 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0004016 decreased bone mass PMID: 16234973 
Esr1tm1.1Lja|Esr1tm1.1Mma Esr1tm1.1Lja/Esr1tm1.1Mma
involves: 129P2/OlaHsd * 129S2/SvPas * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0004016 decreased bone mass PMID: 16234973 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0010124 decreased bone mineral content PMID: 10805804 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0010124 decreased bone mineral content PMID: 10805804 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0010121 decreased bone mineral density PMID: 10805804 
Ctsk+|Ctsktm1(cre)Ska|Esr1tm1Mma Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:107823  MGI:1352467  MP:0010121 decreased bone mineral density PMID: 17803905 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0010121 decreased bone mineral density PMID: 16234973 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6
MGI:1352467  MP:0010121 decreased bone mineral density PMID: 16234973 
Esr1tm1.1Lja|Esr1tm1.1Mma Esr1tm1.1Lja/Esr1tm1.1Mma
involves: 129P2/OlaHsd * 129S2/SvPas * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0010121 decreased bone mineral density PMID: 16234973 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0010121 decreased bone mineral density PMID: 10805804 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0004991 decreased bone strength PMID: 10805804 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008075 decreased CD4-positive T cell number PMID: 11380688 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0008075 decreased CD4-positive T cell number PMID: 11380688 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008079 decreased CD8-positive T cell number PMID: 11380688 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0008079 decreased CD8-positive T cell number PMID: 11380688 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0005181 decreased circulating estradiol level PMID: 17495854 
Esr1tm1Ksk|Esr2tm1Unc|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0002790 decreased circulating follicle stimulating hormone level PMID: 12855748 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0002790 decreased circulating follicle stimulating hormone level PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0004701 decreased circulating insulin-like growth factor I level PMID: 10558910  10805804 
Esr1tm1.1Lja|Esr1tm1.1Mma Esr1tm1.1Lja/Esr1tm1.1Mma
involves: 129P2/OlaHsd * 129S2/SvPas * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0004701 decreased circulating insulin-like growth factor I level PMID: 16234973 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0004701 decreased circulating insulin-like growth factor I level PMID: 10805804 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0002773 decreased circulating luteinizing hormone level PMID: 19439729 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0002773 decreased circulating luteinizing hormone level PMID: 19423761 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0002773 decreased circulating luteinizing hormone level PMID: 12855748 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0005185 decreased circulating progesterone level PMID: 12351685 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0005121 decreased circulating prolactin level PMID: 10919287 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0002780 decreased circulating testosterone level PMID: 17495854 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0002680 decreased corpora lutea number PMID: 19439729 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0002680 decreased corpora lutea number PMID: 19423761 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0004890 decreased energy expenditure PMID: 11070086 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0008335 decreased gonadotroph cell number PMID: 19439729 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002834 decreased heart weight PMID: 10805804 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0008215 decreased immature B cell number PMID: 9647203 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6N
MGI:1352467  MP:0008215 decreased immature B cell number PMID: 10875230 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0008332 decreased lactotroph cell number PMID: 9171231 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0004686 decreased length of long bones PMID: 10558910 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0001935 decreased litter size PMID: 19439729 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0006396 decreased long bone epiphyseal plate size PMID: 14753739 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0005631 decreased lung weight PMID: 10805804 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0004901 decreased male germ cell number PMID: 10976058 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0004901 decreased male germ cell number PMID: 10976058 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0004901 decreased male germ cell number PMID: 18755802 
Esr1tm1Ksk|Esr2tm1Unc|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0004901 decreased male germ cell number PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0008211 decreased mature B cell number PMID: 9647203 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6N
MGI:1352467  MP:0008211 decreased mature B cell number PMID: 10875230 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0004989 decreased osteoblast cell number PMID: 15283680 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0003355 decreased ovulation rate PMID: 12351685 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0008874 decreased physiological sensitivity to xenobiotic PMID: 11784006 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0008874 decreased physiological sensitivity to xenobiotic PMID: 18339713 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0004953 decreased spleen weight PMID: 11380688 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0004852 decreased testis weight PMID: 8248223  8895349 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0004852 decreased testis weight PMID: 18755802 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6N
MGI:1352467  MP:0000715 decreased thymocyte number PMID: 10510352 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6N
MGI:1352467  MP:0004956 decreased thymus weight PMID: 10510352 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0004905 decreased uterus weight PMID: 10558910 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0004905 decreased uterus weight PMID: 11784006  17495854 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6
MGI:1352467  MP:0004905 decreased uterus weight PMID: 16234973 
Esr1tm1.1Lja|Esr1tm1.1Mma Esr1tm1.1Lja/Esr1tm1.1Mma
involves: 129P2/OlaHsd * 129S2/SvPas * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0004905 decreased uterus weight PMID: 16234973 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0004905 decreased uterus weight PMID: 11557741 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008893 detached sperm flagellum PMID: 8895349 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0009140 dilated efferent ductules of testis PMID: 10670526  11698654  9393999 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0006423 dilated rete testis PMID: 8895349 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0006423 dilated rete testis PMID: 11698654  9393999 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0009257 dilated seminiferous tubules PMID: 8895349 
Esr1tm1Ksk|Esr2tm1Unc|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0009257 dilated seminiferous tubules PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * 129S6/SvEvTac
MGI:1352467  MP:0009257 dilated seminiferous tubules PMID: 12855748 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0001123 dilated uterus PMID: 17046690 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0008995 early reproductive senescence PMID: 19423761 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0009359 endometrium atrophy PMID: 17046690 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0009092 endometrium hyperplasia PMID: 12351685 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0009251 enlarged endometrial glands PMID: 12351685 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0004906 enlarged uterus PMID: 12351685 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0009856 failure of ejaculation PMID: 11114183  9037078 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0009856 failure of ejaculation PMID: 11114183 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0001728 failure of embryo implantation PMID: 12297545 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001926 female infertility PMID: 8248223 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0001926 female infertility PMID: 10600740 
Esr1tm1Gsc|Tg(Camk2a-cre)2Gsc Esr1tm1Gsc/Esr1tm1Gsc,Tg(Camk2a-cre)2Gsc/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
MGI:1352467  MGI:2181425  MP:0001926 female infertility PMID: 17046690 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0001926 female infertility PMID: 18339713 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0001926 female infertility PMID: 12351685 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0001926 female infertility PMID: 10976058 
Esr1tm1.2Mma|Tg(Cga-cre)3Sac Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cga-cre)3Sac/0
involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL
MGI:1352467  MGI:2180056  MP:0001926 female infertility PMID: 17947360 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0001926 female infertility PMID: 18953638 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0001926 female infertility PMID: 19439729 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0001926 female infertility PMID: 19423761 
Esr1tm2.1Gsc Esr1tm2.1Gsc/Esr1tm2.1Gsc
involves: 129P2/OlaHsd * C57BL/6
MGI:1352467  MP:0001926 female infertility PMID: 19574448 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002743 glomerulonephritis PMID: 14745006 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0001654 hepatic necrosis PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001399 hyperactivity PMID: 9037078 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0005498 hyporesponsive to tactile stimuli PMID: 19285805 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0000242 impaired fertilization PMID: 8895349 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0005293 impaired glucose tolerance PMID: 19366879 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0005293 impaired glucose tolerance PMID: 11070086 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0003357 impaired granulosa cell differentiation PMID: 18339713 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0003357 impaired granulosa cell differentiation PMID: 10976058 
Esr1+|Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1+,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0003357 impaired granulosa cell differentiation PMID: 10976058 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0001129 impaired ovarian folliculogenesis PMID: 10342864 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0001129 impaired ovarian folliculogenesis PMID: 18953638 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0004000 impaired passive avoidance behavior PMID: 11074057 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001356 increased aggression towards females PMID: 9832446 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0001356 increased aggression towards females PMID: 11114183 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0004762 increased anti-double stranded DNA antibody level PMID: 14745006 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0001257 increased body length PMID: 14753739 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0001264 increased body size PMID: 18339713 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001260 increased body weight PMID: 10558910 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0001260 increased body weight PMID: 11784006  17495854 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0001260 increased body weight PMID: 18339713 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0001260 increased body weight PMID: 11070086 
Esr1tm1Ksk|Esr2tm1Unc|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0001260 increased body weight PMID: 12855748 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0010120 increased bone mineral density PMID: 16234973 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6
MGI:1352467  MP:0010120 increased bone mineral density PMID: 16234973 
Ctsk+|Ctsktm1(cre)Ska|Esr1tm1Mma Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:107823  MGI:1352467  MP:0004992 increased bone resorption PMID: 17803905 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0005178 increased circulating cholesterol level PMID: 11095962 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0005178 increased circulating cholesterol level PMID: 11095962 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0005182 increased circulating estradiol level PMID: 8584021 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0005182 increased circulating estradiol level PMID: 11784006 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0005182 increased circulating estradiol level PMID: 18339713 
Esr1tm1.1Lja|Esr1tm1.1Mma Esr1tm1.1Lja/Esr1tm1.1Mma
involves: 129P2/OlaHsd * 129S2/SvPas * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0005182 increased circulating estradiol level PMID: 16234973 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0005182 increased circulating estradiol level PMID: 19439729 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * 129S6/SvEvTac
MGI:1352467  MP:0005182 increased circulating estradiol level PMID: 12855748 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0005182 increased circulating estradiol level PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0005559 increased circulating glucose level PMID: 19366879 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001556 increased circulating HDL cholesterol level PMID: 11095962 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0001556 increased circulating HDL cholesterol level PMID: 11095962 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0005669 increased circulating leptin level PMID: 11095962 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0005669 increased circulating leptin level PMID: 11095962 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0001751 increased circulating luteinizing hormone level PMID: 10600740 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0001751 increased circulating luteinizing hormone level PMID: 18339713 
Esr1tm2Ksk Esr1tm2Ksk/Esr1tm2Ksk
involves: C57BL/6
MGI:1352467  MP:0001751 increased circulating luteinizing hormone level PMID: 14583652 
Esr1tm1.2Awo|Tg(Cga-cre)1Awo Esr1tm1.2Awo/Esr1tm1.2Awo,Tg(Cga-cre)1Awo/0
involves: C57BL/6 * SJL
MGI:1352467  MGI:4360771  MP:0001751 increased circulating luteinizing hormone level PMID: 19439729 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002781 increased circulating testosterone level PMID: 8895349 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0002781 increased circulating testosterone level PMID: 17495854 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0002781 increased circulating testosterone level PMID: 18339713 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0002781 increased circulating testosterone level PMID: 18755802 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0002781 increased circulating testosterone level PMID: 19423761 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0005091 increased double-positive T cell number PMID: 11380688 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0005091 increased double-positive T cell number PMID: 11380688 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0009288 increased epididymal fat pad weight PMID: 11070086 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0009285 increased gonadal fat pad weight PMID: 11095962 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0009285 increased gonadal fat pad weight PMID: 18339713 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0009285 increased gonadal fat pad weight PMID: 11095962 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0008334 increased gonadotroph cell number PMID: 19423761 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008502 increased IgG3 level PMID: 14745006 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0009292 increased inguinal fat pad weight PMID: 11070086 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0009296 increased mammary fat pad weight PMID: 18339713 
Esr1tm1Ksk|Tg(MMTV-Erbb2)NK1Mul Esr1tm1Ksk/Esr1tm1Ksk,Tg(MMTV-Erbb2)NK1Mul/0
involves: 129P2/OlaHsd * C57BL/6J * FVB/N
MGI:1352467  MGI:3513809  MP:0010299 increased mammary gland tumor incidence PMID: 12019156 
Ctsk+|Ctsktm1(cre)Ska|Esr1tm1Mma Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:107823  MGI:1352467  MP:0004984 increased osteoclast cell number PMID: 17803905 
Esr1tm1.1Scma|Lyz2+|Lyz2tm1(cre)Ifo Esr1tm1.1Scma/Esr1tm1.1Scma,Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
MGI:1352467  MGI:96897  MP:0004984 increased osteoclast cell number PMID: 20053716 
Esr1tm1Ksk|Esr2tm1Unc|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0008000 increased ovary tumor incidence PMID: 12855748 
Esr1tm1Ksk|Esr2tm1Unc|Inha+|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc,Inhatm1Bay/Inha+
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:109392  MGI:1352467  MGI:96569  MP:0008000 increased ovary tumor incidence PMID: 12855748 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0008000 increased ovary tumor incidence PMID: 12855748 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0009300 increased parametrial fat pad weight PMID: 11070086 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008097 increased plasma cell number PMID: 14745006 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0009302 increased renal fat pad weight PMID: 11070086 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0009304 increased retroperitoneal fat pad weight PMID: 11095962 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0009304 increased retroperitoneal fat pad weight PMID: 11095962 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0008481 increased spleen germinal center number PMID: 14745006 
Esr1tm1.1Mma|Ldlrtm1Her Esr1tm1.1Mma/Esr1tm1.1Mma,Ldlrtm1Her/Ldlrtm1Her
involves: 129S2/SvPas * 129S7/SvEvBrd
MGI:1352467  MGI:96765  MP:0005339 increased susceptibility to atherosclerosis PMID: 19188600 
Esr1tm1Arnal|Ldlrtm1Her Esr1tm1Arnal/Esr1tm1Arnal,Ldlrtm1Her/Ldlrtm1Her
involves: 129S7/SvEvBrd
MGI:1352467  MGI:96765  MP:0005339 increased susceptibility to atherosclerosis PMID: 19188600 
Apoetm1Bres|Esr1tm1Ksk Apoetm1Bres/Apoetm1Bres,Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Apoe Esr1
MGI:1352467  MGI:88057  MP:0005339 increased susceptibility to atherosclerosis PMID: 11160157 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0009371 increased thecal cell number PMID: 18339713 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0009371 increased thecal cell number PMID: 19423761 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0010024 increased total body fat amount PMID: 11095962 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0010024 increased total body fat amount PMID: 18953638 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0010024 increased total body fat amount PMID: 11095962 
Esr1tm1Ksk|Tg(Wnt1)1Hev Esr1tm1Ksk/Esr1tm1Ksk,Tg(Wnt1)1Hev/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:1890060  MP:0009828 increased tumor latency PMID: 10213494 
Esr1tm1Ksk|Tg(MMTV-Erbb2)NK1Mul Esr1tm1Ksk/Esr1tm1Ksk,Tg(MMTV-Erbb2)NK1Mul/0
involves: 129P2/OlaHsd * C57BL/6J * FVB/N
MGI:1352467  MGI:3513809  MP:0009828 increased tumor latency PMID: 12019156 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ
MGI:1352467  MP:0004904 increased uterus weight PMID: 12351685 
Esr1+|Esr1tm1.1Lja Esr1tm1.1Lja/Esr1+
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
MGI:1352467  MP:0004904 increased uterus weight PMID: 16234973 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002574 increased vertical activity PMID: 9037078 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0000008 increased white adipose tissue amount PMID: 11070086 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0009130 increased white fat cell number PMID: 11070086 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0009118 increased white fat cell size PMID: 11070086 
Esr1tm1Arnal Esr1tm1Arnal/Esr1tm1Arnal
involves: C57BL/6
MGI:1352467  MP:0001924 infertility PMID: 19188600 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0005331 insulin resistance PMID: 11095962 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0005331 insulin resistance PMID: 19366879 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1
MGI:1352467  MP:0005331 insulin resistance PMID: 11070086 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0005331 insulin resistance PMID: 11095962 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0000069 kyphoscoliosis PMID: 12855748 
Esr1tm1Ksk|Inhatm1Bay Esr1tm1Ksk/Esr1tm1Ksk,Inhatm1Bay/Inhatm1Bay
involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd
MGI:1352467  MGI:96569  MP:0001860 liver inflammation PMID: 12855748 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0004348 long femur PMID: 14753739 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001925 male infertility PMID: 8895349 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0001925 male infertility PMID: 10600740 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0001925 male infertility PMID: 11698654 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0001925 male infertility PMID: 10976058 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0001925 male infertility PMID: 18755802 
Esr1tm1Ksk|Tg(Wnt1)1Hev Esr1tm1Ksk/Esr1tm1Ksk,Tg(Wnt1)1Hev/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:1890060  MP:0001883 mammary adenocarcinoma PMID: 10213494 
Esr1tm1Ksk|Tg(Wnt1)1Hev Esr1tm1Ksk/Esr1tm1Ksk,Tg(Wnt1)1Hev/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:1890060  MP:0001884 mammary gland alveolar hyperplasia PMID: 10213494 
Esr1tm1Ksk|Tg(Wnt1)1Hev Esr1tm1Ksk/Esr1tm1Ksk,Tg(Wnt1)1Hev/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:1890060  MP:0001885 mammary gland duct hyperplasia PMID: 10213494 
Esr1tm1Ksk|Tg(Wnt1)1Hev Esr1tm1Ksk/Esr1tm1Ksk,Tg(Wnt1)1Hev/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
MGI:1352467  MGI:1890060  MP:0000630 mammary gland hyperplasia PMID: 10213494 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0001261 obese PMID: 11095962 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0001261 obese PMID: 18953638 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J
MGI:109392  MGI:1352467  MP:0001261 obese PMID: 11095962 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0002687 oligozoospermia PMID: 8248223  8895349 
Esr1tm1Ksk|Esr2tm1Unc Esr1tm1Ksk/Esr1tm1Ksk,Esr2tm1Unc/Esr2tm1Unc
involves: 129P2/OlaHsd
MGI:109392  MGI:1352467  MP:0002687 oligozoospermia PMID: 10600740 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0002687 oligozoospermia PMID: 10670526 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0002687 oligozoospermia PMID: 18755802 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
B6.129P2-Esr1/J
MGI:1352467  MP:0002687 oligozoospermia PMID: 18755802 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-cre)ACmk/0
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MGI:3807211  MP:0009093 oocyte degeneration PMID: 19423761 
Ctsk+|Ctsktm1(cre)Ska|Esr1tm1Mma Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:107823  MGI:1352467  MP:0000066 osteoporosis PMID: 17803905 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd * C57BL/6J
MGI:1352467  MP:0009444 ovarian follicular cyst PMID: 8248223 
Esr1tm1Ksk Esr1tm1Ksk/Esr1tm1Ksk
involves: 129P2/OlaHsd
MGI:1352467  MP:0009444 ovarian follicular cyst PMID: 10342864  10919287  11784006 
Esr1tm1Geog Esr1tm1Geog/Esr1tm1Geog
involves: 129X1/SvJ * C57BL/6
MGI:1352467  MP:0002016 ovary cysts PMID: 18339713 
Esr1tm1.1Mma Esr1tm1.1Mma/Esr1tm1.1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:1352467  MP:0002016 ovary cysts PMID: 10976058 
Esr1tm1.1Mma|Esr2tm1Mma Esr1tm1.1Mma/Esr1tm1.1Mma,Esr2tm1Mma/Esr2tm1Mma
involves: 129S2/SvPas * C57BL/6 * SJL
MGI:109392  MGI:1352467  MP:0002016 ovary cysts PMID: 10976058 
Esr1tm1.2Mma|Tg(Cga-cre)3Sac Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cga-cre)3Sac/0
involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL
MGI:1352467  MGI:2180056  MP:0002016 ovary cysts PMID: 17947360 
Esr1tm1Syeh|Tg(ACTB-cre)2Mrt Esr1tm1Syeh/Esr1tm1Syeh,Tg(ACTB-cre)2Mrt/0
involves: 129X1/SvJ * FVB/N
MGI:1352467  MGI:2176049  MP:0002016 ovary cysts PMID: 18953638 
Esr1tm1.2Mma|Tg(Cyp17a1-cre)ACmk Esr1tm1.2Mma/Esr1tm1.2Mma,Tg