levallorphan

Ligand id: 7209

Name: levallorphan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 23.47
Molecular weight 283.19
XLogP 4.3
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
μ receptor Antagonist Antagonist 8.8 – 9.3 pKi - 1
pKi 8.8 – 9.3 (Ki 1.69x10-9 – 4.8x10-10 M) [1]
Description: Competition binding assay- the calculated Ki varies depending on the radioligand used.