levallorphan

Ligand id: 7209

Name: levallorphan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 23.47
Molecular weight 283.19
XLogP 4.3
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used an an antidote to opioid-induced respiratory depression. There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.
Mechanism Of Action and Pharmacodynamic Effects
Levallorphan is an antagonist of the μ receptor (OPRM1), but is an agonist of the κ receptor (OPRK1).