pomalidomide

Ligand id: 7348

Name: pomalidomide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 109.57
Molecular weight 273.07
XLogP -0.76
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Pomalidomide displaces a Cy5-conjugated cereblon modulating compound from the binding pocket of CRBN with an IC50 of 1200nM [4].