Ligand id: 7510

Name: BIC1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 92.55
Molecular weight 340.08
XLogP 5.56
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
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Target Type Action Affinity Units Concentration range (M) Reference
bromodomain containing 2 Inhibitor Inhibition 4.6 pKd - 1
pKd 4.6 (Kd 2.8x10-5 M) [1]
Description: Binding to recombinant BRD2-BD1 protein.