Ligand id: 7515

Name: BzT-7

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 33.95
Molecular weight 323.09
XLogP 5.38
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
bromodomain containing 4 Hs Inhibitor Inhibition 6.2 pKd - 1
pKd 6.2 (Kd 6.4x10-7 M) [1]
Description: Measuring the dissociation constant for the compound's interaction with BD1 of BRD4.