BzT-7

Ligand id: 7515

Name: BzT-7

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 33.95
Molecular weight 323.09
XLogP 5.38
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
8-chloro-1,4-dimethyl-6-phenyl-[1,2,4]triazolo[4,3-a][1,3,4]benzotriazepine
Database Links
ChEMBL Ligand CHEMBL1958337
GtoPdb PubChem SID 187051817
PubChem CID 20350618
RCSB PDB Ligand 08K
Search Google for chemical match using the InChIKey UYIVCPRWMLOCSB-UHFFFAOYSA-N
Search Google for chemicals with the same backbone UYIVCPRWMLOCSB
Search UniChem for chemical match using the InChIKey UYIVCPRWMLOCSB-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone UYIVCPRWMLOCSB
SynPHARM 79910 (in complex with bromodomain containing 4)
Comments
BzT‑7 is a benzotriazepine which functions as an inhibitor of BET domain containing BRDs (BRDs 2, 3 and 4) [1].