Ligand id: 7540

Name: brodalumab

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
BLAST searches using the peptide sequences of the heavy and light chains of brodalumab link to patent US7767206 [7], and monoclonal antibody clone AMH14/AML14.
Selectivity at human catalytic receptors
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Target Type Action Affinity Units Concentration range (M) Reference
Interleukin 17 receptor A Antibody Binding 9.2 pKd - 7
pKd 9.2 (Kd 6.9x10-10 M) [7]