brodalumab

Ligand id: 7540

Name: brodalumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
BLAST searches using the peptide sequences of the heavy and light chains of brodalumab link to patent US7767206 [7], and monoclonal antibody clone AMH14/AML14.
Selectivity at catalytic receptors
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Target Sp. Type Action Affinity Units Concentration range (M) Reference
Interleukin 17 receptor A Hs Antibody Binding 9.2 pKd - 7
pKd 9.2 (Kd 6.9x10-10 M) [7]