AZD1981

Ligand id: 7680

Name: AZD1981

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 96.63
Molecular weight 388.06
XLogP 3.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Data for 48 analogues from the reference given are listed in PubChem BioAssay 630011
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
DP2 receptor Hs Antagonist Antagonist 8.4 pIC50 - 2
pIC50 8.4 (IC50 4.3x10-9 M) [2]
Description: Displacement of [3H]PGD2 from human CRTH2 receptor