Ligand id: 7827

Name: AZD7687

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 106.17
Molecular weight 367.19
XLogP 4.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Bioactivity in the table below is associated with the stereoisomer with ChEMBL ID CHEMBL2178953.
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
diacylglycerol O-acyltransferase 1 Hs Inhibitor Inhibition 7.1 pIC50 - 1
pIC50 7.1 (IC50 8x10-8 M) [1]
Description: Measured using purified human DGAT1