Synonyms: REGN-910 | REGN910 | SAR307746
Compound class:
Antibody
Comment: Nesvacumab is a fully human monoclonal antibody that targets angiopoietin-2 (ANGPT2, aka ANG2), being investigated as an antiangiogenic anti-tumour agent.
Peptide sequences for this antibody are available from its IMGT/mAb-DB record. |
Bioactivity Comments |
Nesvacumab is reported to disrupt Tie2-mediated signalling in preclinical studies [1]. |
Selectivity at ligand targets | ||||||||||||||||||||||||||||||||||
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