Ligand id: 1064

Name: (-)-baclofen

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 63.32
Molecular weight 213.06
XLogP 1.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
As one of the enantiomers in the approved drug baclofen, this skeletal muscle relaxant is used to reduce the frequency of muscle spasms and muscle spasticity associated with spinal chord injury.