(-)-baclofen

Ligand id: 1064

Name: (-)-baclofen

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 63.32
Molecular weight 213.06
XLogP 1.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Froestl W, Mickel SJ. (1997)
Chemistry of GABAB modulators.  in  The GABA Receptors
Edited by Enna SJ, Bowery NG Humana Press. 271-296  [ISBN:0896034585]
2. Kaupmann K, Huggel K, Heid J, Flor PJ, Bischoff S, Mickel SJ, McMaster G, Angst C, Bittiger H, Froestl W, Bettler B. (1997)
Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors.
Nature386: 239-246. [PMID:9069281]