pyrilamine

Ligand id: 1227

Name: pyrilamine

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View more information in the IUPHAR Pharmacology Education Project: mepyramine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 28.6
Molecular weight 285.18
XLogP 3.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Pyrilamine suppresses the symptoms of allergic rhinitis. This drug does not have marketing approval in the US or European Union. Other national approval agencies may have granted marketing authorisation. In some countries pyrilamine may only be used in veterinary practice.
Mechanism Of Action and Pharmacodynamic Effects
Histamine H1 receptor antagonist.
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