pyrilamine

Ligand id: 1227

Name: pyrilamine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 28.6
Molecular weight 285.18
XLogP 3.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine
International Nonproprietary Names
INN number INN
106 mepyramine
Synonyms
Anthisan® | mepiramine | mepyramine maleate | pyrilamine tannate | Pyrlex®
Database Links
CAS Registry No. 91-84-9 (source: ChEBI)
ChEBI CHEBI:6762
ChEMBL Ligand CHEMBL511
DrugBank Ligand DB06691
PubChem CID 4992
Search Google for chemical match using the InChIKey YECBIJXISLIIDS-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YECBIJXISLIIDS
Search PubMed clinical trials mepyramine
Search PubMed titles mepyramine
Search PubMed titles/abstracts mepyramine
Search UniChem for chemical match using the InChIKey YECBIJXISLIIDS-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YECBIJXISLIIDS
Wikipedia Mepyramine
Comments
Pyrilamine is a first generation antihistamine, but it crosses the blood-brain barrier easily and causes substantial drowsiness.