oxymetazoline

Ligand id: 124

Name: oxymetazoline

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 44.62
Molecular weight 260.19
XLogP 3.55
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Sympathomimetic used to relieve nasal congestion and eye irritation.
Mechanism Of Action and Pharmacodynamic Effects
Agonism of alpha-adrenergic receptor in the arterioles of the conjunctiva and nasal muscosa produces vasoconstriction. This results in decreased conjunctival congestion in ophthalmic mucosa, while in the nasal mucosa constrction results in decreased blood flow and decreased nasal congestion.
External links