levocabastine

Ligand id: 1586

Name: levocabastine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 64.33
Molecular weight 420.22
XLogP 6.18
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of allergic seasonal conjunctivitis, and as a nasal spray for allergic rhinitis. The US FDA website records this drug as 'Discontinued'.
Mechanism Of Action and Pharmacodynamic Effects
Histamine H1 receptor antagonist which prevents the effects of histamine binding these receptors.